SPIRAL: Significant Process InfeRence Algorithm for single cell RNA-sequencing and spatial transcriptomics

Welcome to SPIRAL


SPIRAL is an algorithm that relies on a Gaussian statistical model to produce a comprehensive overview of significant processes in single cell RNA-seq, spatial transcriptomics or bulk RNA-seq. SPIRAL detects biological processes by identifying the subset of genes involved and the subset of cells, spots or samples.

Here are examples of SPIRAL output for different data sets:





How to cite?

Hadas Biran, Tamar Hashimshony, Yael Mandel-Gutfreund and Zohar Yakhini. SPIRAL: Significant Process InfeRence Algorithm for single cell RNA-sequencing and spatial transcriptomics. (2022). (in review)